Norman Hascoe Distinguished Lecture Series

Microfabrication and X-ray Scattering: New Tools for Studying Protein and RNA Folding

Lois Pollack
School of Applied and Engineering Physics
Cornell University

Large biological molecules like proteins and RNA, carry out their functions by folding to well-defined three-dimensional structures. We are interested in the physical interactions that direct this self-assembly process. By combining microfabricated flow cells with synchrotron x-ray scattering, we have gained insight into the earliest steps of protein and RNA folding. A recent series of experiments indicates that the critical, first stage of RNA folding is dominated by electrostatic interactions.

Monday, October 24, 2005

P-36

(Refreshments will follow, with a panel discussion at 5:30 PM.)


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